BDBM50271030 3'-carbamoylbiphenyl-3-yl naphthalen-2-ylmethylcarbamate::CHEMBL483697::Naphthalen-2-ylmethylcarbamic Acid 3'-Carbamoylbiphenyl-3-yl Ester

SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCc2ccc3ccccc3c2)c1

InChI Key InChIKey=HSPABSYTWRUCGU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50271030   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50271030(Naphthalen-2-ylmethylcarbamic Acid 3'-Carbamoylbip...)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of FAAH in rat brain membrane assessed as [3H]anandamide hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50271030(Naphthalen-2-ylmethylcarbamic Acid 3'-Carbamoylbip...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of monoglyceride lipase in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50271030(Naphthalen-2-ylmethylcarbamic Acid 3'-Carbamoylbip...)
Affinity DataIC50: 0.631nMAssay Description:Displacement of [3H]-anandamide from rat brain FAAH after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50271030(Naphthalen-2-ylmethylcarbamic Acid 3'-Carbamoylbip...)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed