BDBM50270888 CHEMBL525201

SMILES CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc4cnc[nH]4)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc5ccccc5)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc6ccc(O)cc6)C(=O)N7CCC[C@H]7C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N8CCC[C@H]8C(O)=O

InChI Key InChIKey=WGJHMCNUSNAKEE-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50270888   

TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50270888(CHEMBL525201)
Affinity DataKd:  720nMpH: 6.0Assay Description:Binding affinity to human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50270888(CHEMBL525201)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human IgG binding to soluble human FcRn by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed