BDBM50270784 CHEMBL499790::GGGCVTGHFGGIYCNYQ

SMILES CC[C@H](C)[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(O)=O)NC(=O)CNC(=O)CNC(=O)CN)C(C)C)[C@H](C)O

InChI Key InChIKey=RNDLHDADENIYQB-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50270784   

TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50270784(GGGCVTGHFGGIYCNYQ | CHEMBL499790)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human IgG binding to soluble human FcRn by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50270784(GGGCVTGHFGGIYCNYQ | CHEMBL499790)
Affinity DataKd:  5.20E+3nMpH: 6.0Assay Description:Binding affinity to human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50270784(GGGCVTGHFGGIYCNYQ | CHEMBL499790)
Affinity DataKd:  3.50E+4nMpH: 7.4Assay Description:Binding affinity to human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed