BDBM50270611 4-(6,7-Dimethoxy-9H-pyrimido[4,5-b]indol-4-yl)-piperazine-1-carbothioic acid [4-(pyrimidin-2-ylsulfamoyl)-phenyl]-amide::CHEMBL456689

SMILES COc1cc2[nH]c3ncnc(N4CCN(CC4)C(=S)Nc4ccc(cc4)S(=O)(=O)Nc4ncccn4)c3c2cc1OC

InChI Key InChIKey=URSWGFSZIPXVPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50270611   

TargetAurora kinase A(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50270611(4-(6,7-Dimethoxy-9H-pyrimido[4,5-b]indol-4-yl)-pip...)
Affinity DataIC50: 94nMAssay Description:Inhibition of aurora kinase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed