BDBM50270495 CHEMBL4126890

SMILES [H][C@@]12CCC(=C)[C@H](CC3=C(O)C(=O)C4=C(C3=O)[C@@]35C=C[C@@H](O)[C@H](O)[C@]3(C4)C(=O)c3c(O)cc(C)cc3C5=O)[C@@]1(C)CC[C@@H](O)C2(C)C

InChI Key InChIKey=ZSZWRYTWPTULOO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50270495   

TargetProteasome subunit beta type-5(Human)
Hirosaki University

Curated by ChEMBL
LigandPNGBDBM50270495(CHEMBL4126890)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human erythrocyte 20s proteasome chymotrypsin-like activity using Suc-LLVY-MCA as substrate pretreated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Hirosaki University

Curated by ChEMBL
LigandPNGBDBM50270495(CHEMBL4126890)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human erythrocyte 20s proteasome trypsin-like activity using Boc-LRR-MCA as substrate pretreated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Hirosaki University

Curated by ChEMBL
LigandPNGBDBM50270495(CHEMBL4126890)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of human erythrocyte 20s proteasome caspase-like activity using Z-LLE-MCA as substrate pretreated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2020
Entry Details Article
PubMed