BDBM50270030 2-Amino-N-((S)-1-benzyl-3-diazo-2-oxo-propyl)-acetamide::CHEMBL448143

SMILES NCC(=O)N[C@@H](Cc1ccccc1)C(=O)[CH-][N+]#N

InChI Key InChIKey=CBOIZHHBFFTMCQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50270030   

TargetDipeptidyl peptidase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50270030(2-Amino-N-((S)-1-benzyl-3-diazo-2-oxo-propyl)-acet...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant cathepsin C after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50270030(2-Amino-N-((S)-1-benzyl-3-diazo-2-oxo-propyl)-acet...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant cathepsin B after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50270030(2-Amino-N-((S)-1-benzyl-3-diazo-2-oxo-propyl)-acet...)
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of human recombinant cathepsin L after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetPro-cathepsin H(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50270030(2-Amino-N-((S)-1-benzyl-3-diazo-2-oxo-propyl)-acet...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human recombinant cathepsin H after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50270030(2-Amino-N-((S)-1-benzyl-3-diazo-2-oxo-propyl)-acet...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human Cathepsin C using Ala-4-[ 125 I]Phe-DMK as substrate preincubated for 30 mins followed by substrate addition measured after 6 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed