BDBM50269998 (S)-2-((R)-5-chloro-8-hydroxy-3-methyl-1-oxoisochroman-7-carboxamido)-3-phenylpropanoate

SMILES C[C@@H]1Cc2c(Cl)cc(C(=O)N[C@@H](Cc3ccccc3)C([O-])=O)c(O)c2C(=O)O1

InChI Key InChIKey=RWQKHEORZBHNRI-UHFFFAOYSA-M

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50269998   

TargetL-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50269998((S)-2-((R)-5-chloro-8-hydroxy-3-methyl-1-oxoisochr...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant MBP-tagged MshC assessed as formation of fluorescently labeled Cys-GlcN-Ins by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269998((S)-2-((R)-5-chloro-8-hydroxy-3-methyl-1-oxoisochr...)
Affinity DataKi:  6.31E+3nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSolute carrier family 22 member 20(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50269998((S)-2-((R)-5-chloro-8-hydroxy-3-methyl-1-oxoisochr...)
Affinity DataKi:  4.90E+4nMAssay Description:Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed