BDBM50269978 Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Fly-Tyr::CHEMBL526677

SMILES CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)C(C)(C)NC(=O)[C@@H](NC(=O)C(C)(C)N)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCNC(=O)c2ccccc2C3=C4C=CC(=O)C=C4Oc5cc(O)ccc35)C(=O)N[C@@H](Cc6ccc(O)cc6)C(N)=O

InChI Key InChIKey=OGWIJMCFVCUOPC-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50269978   

TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269978(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Fl...)
Affinity DataIC50: 13.5nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269978(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Fl...)
Affinity DataEC50:  7.20nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in SAOS2 cells assessed as cAMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50269978(Aib-Val-Aib-Glu-lle-Gln-Leu-Nle-His-Gln-Arg-Ala-Fl...)
Affinity DataEC50:  0.920nMAssay Description:Activity at human PTH/PTH-related peptide receptor expressed in HEK293 cells assessed as induction of luciferase activity by CRE-luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed