BDBM50269859 2,2,2-trifluoroacetate; 5-(2-azaniumyl-2-{[(1S,2S)-1-cyano-2-phenylcyclopropyl]carbamoyl}ethyl)-1,3-thiazol-3-ium

SMILES [NH3+]C(Cc1c[nH+]cs1)C(=O)N[C@]1(C[C@H]1c1ccccc1)C#N

InChI Key InChIKey=ZDIWELBONJHKGV-UHFFFAOYSA-P

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50269859   

TargetNeutrophil elastase(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50269859(2,2,2-trifluoroacetate; 5-(2-azaniumyl-2-{[(1S,2S)...)
Affinity DataIC50: 7.93E+3nMAssay Description:Inhibition of neutrophil elastase activation in beta-estradiol differentiated mouse EcoM-G cells after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCathepsin G(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50269859(2,2,2-trifluoroacetate; 5-(2-azaniumyl-2-{[(1S,2S)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of cathepsin G activation in beta-estradiol differentiated mouse EcoM-G cells after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50269859(2,2,2-trifluoroacetate; 5-(2-azaniumyl-2-{[(1S,2S)...)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant cathepsin C after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed