BDBM50269778 CHEMBL4103182

SMILES O[C@@]1(Cc2cc(on2)-c2ccc(=O)[nH]c2)CC[C@H](Cc2ccc(Cl)cc2)CC1

InChI Key InChIKey=BSUQWSWGPSJBIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269778   

TargetGlutamate receptor ionotropic, NMDA 2B(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50269778(CHEMBL4103182)
Affinity DataIC50: 63nMAssay Description:Antagonist activity at mouse NR2B expressed in Hek293 cells co-expressing mouse NR1 assessed as inhibition of glutamic acid/glycine-induced intracell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50269778(CHEMBL4103182)
Affinity DataIC50: 316nMAssay Description:Displacement of [3H]-ifenprodil from NR2B in Wistar rat brain membrane after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2020
Entry Details Article
PubMed