BDBM50269759 CHEMBL4093543

SMILES COc1ccc(C[C@H]2CC[C@](O)(Cc3cc(on3)-c3cn[nH]c3)CC2)cc1

InChI Key InChIKey=FPZWRKGJZUKONT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269759   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50269759(CHEMBL4093543)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]-ifenprodil from NR2B in Wistar rat brain membrane after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50269759(CHEMBL4093543)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at mouse NR2B expressed in Hek293 cells co-expressing mouse NR1 assessed as inhibition of glutamic acid/glycine-induced intracell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2020
Entry Details Article
PubMed