BDBM50269706 CHEMBL4088418

SMILES CN(C1CCN(C)CC1)C(=O)c1cn(C)c(=O)c2[nH]ccc12

InChI Key InChIKey=WSBRDLIMEGQZPA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50269706   

TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50269706(CHEMBL4088418)
Affinity DataIC50: 780nMAssay Description:Inhibition of recombinant human N-terminal His6-FLAG-tagged CECR2 expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 9(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50269706(CHEMBL4088418)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-FLAG-tagged BRD9 (unknown origin) expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50269706(CHEMBL4088418)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-FLAG-tagged TAF1 bromodomain 2 (unknown origin) expressed in Rosetta2 (DE3) pLysS cells after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50269706(CHEMBL4088418)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-FLAG-tagged BRD4 bromodomain 1 expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50269706(CHEMBL4088418)
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-FLAG-tagged BRD4 bromodomain 2 (unknown origin) expressed in Rosetta2 (DE3) pLysS cells after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2020
Entry Details Article
PubMed