BDBM50269645 3,4-dihydroxyxanthone::CHEMBL446323::US9114126, MB2

SMILES Oc1ccc2c(oc3ccccc3c2=O)c1O

InChI Key InChIKey=YFVCSEXMOBEPQB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50269645   

TargetPotassium-transporting ATPase alpha chain 1(Pig)
The University of Toledo

US Patent
LigandPNGBDBM50269645(3,4-dihydroxyxanthone | CHEMBL446323 | US9114126, ...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:The purified Na/K-ATPase was prepared from pig kidney. The specific activities of Na/K-ATPase of various kidney preparations were in the range of 900...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50269645(3,4-dihydroxyxanthone | CHEMBL446323 | US9114126, ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX1 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50269645(3,4-dihydroxyxanthone | CHEMBL446323 | US9114126, ...)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of human COX2 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosinase(Human)
Universidade Dos A£Ores

Curated by ChEMBL
LigandPNGBDBM50269645(3,4-dihydroxyxanthone | CHEMBL446323 | US9114126, ...)
Affinity DataIC50: 5.12E+3nMAssay Description:Inhibition of Tyrosinase (unknown origin) using tyrosine as substrate incubated for 20 mins followed by substrate addition and measured every 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed