BDBM50269058 (1S,2S,5R)-N-hydroxy-5-(2-oxo-2-(piperidin-1-yl)ethyl)-2-(4-phenylpiperazine-1-carbonyl)cyclohexanecarboxamide::CHEMBL496629

SMILES ONC(=O)[C@H]1C[C@H](CC(=O)N2CCCCC2)CC[C@@H]1C(=O)N1CCN(CC1)c1ccccc1

InChI Key InChIKey=SPGSQKKTHWOODB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50269058   

Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50269058((1S,2S,5R)-N-hydroxy-5-(2-oxo-2-(piperidin-1-yl)et...)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50269058((1S,2S,5R)-N-hydroxy-5-(2-oxo-2-(piperidin-1-yl)et...)
Affinity DataIC50: 170nMAssay Description:Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50269058((1S,2S,5R)-N-hydroxy-5-(2-oxo-2-(piperidin-1-yl)et...)
Affinity DataIC50: 165nMAssay Description:Inhibition of human recombinant ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed