BDBM50269002 (1S,2S,5RS)-N-hydroxy-5-(2-morpholino-2-oxoethyl)-2-(4-phenylpiperazine-1-carbonyl)cyclohexanecarboxamide::CHEMBL496825

SMILES ONC(=O)[C@H]1CC(CC(=O)N2CCOCC2)CC[C@@H]1C(=O)N1CCN(CC1)c1ccccc1

InChI Key InChIKey=DSPHOALBCOPTJE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50269002   

Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50269002((1S,2S,5RS)-N-hydroxy-5-(2-morpholino-2-oxoethyl)-...)
Affinity DataIC50: 236nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50269002((1S,2S,5RS)-N-hydroxy-5-(2-morpholino-2-oxoethyl)-...)
Affinity DataIC50: 208nMAssay Description:Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50269002((1S,2S,5RS)-N-hydroxy-5-(2-morpholino-2-oxoethyl)-...)
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed