BDBM50268953 (1S,2S)-N-hydroxy-2-(4-phenylpiperazine-1-carbonyl)cyclohexanecarboxamide::CHEMBL496212

SMILES ONC(=O)[C@H]1CCCC[C@@H]1C(=O)N1CCN(CC1)c1ccccc1

InChI Key InChIKey=UMKOSVICWGLVQX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50268953   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50268953((1S,2S)-N-hydroxy-2-(4-phenylpiperazine-1-carbonyl...)
Affinity DataIC50: 470nMAssay Description:Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50268953((1S,2S)-N-hydroxy-2-(4-phenylpiperazine-1-carbonyl...)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of human recombinant ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50268953((1S,2S)-N-hydroxy-2-(4-phenylpiperazine-1-carbonyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50268953((1S,2S)-N-hydroxy-2-(4-phenylpiperazine-1-carbonyl...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed