BDBM50268952 (2S,3S,5RS)-N-hydroxy-1-methyl-5-(2-oxo-2-(piperidin-1-yl)ethyl)-2-(4-phenylpiperazine-1-carbonyl)piperidine-3-carboxamide::CHEMBL496211

SMILES CN1CC(CC(=O)N2CCCCC2)C[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO

InChI Key InChIKey=VOGZLMQCZGOADJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268952   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50268952((2S,3S,5RS)-N-hydroxy-1-methyl-5-(2-oxo-2-(piperid...)
Affinity DataIC50: 102nMAssay Description:Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50268952((2S,3S,5RS)-N-hydroxy-1-methyl-5-(2-oxo-2-(piperid...)
Affinity DataIC50: 77nMAssay Description:Inhibition of human recombinant ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50268952((2S,3S,5RS)-N-hydroxy-1-methyl-5-(2-oxo-2-(piperid...)
Affinity DataIC50: 81nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed