BDBM50268904 CHEMBL445717::benzyl 5-(2-((3RS,5S,6S)-5-(hydroxycarbamoyl)-6-(3-phenylpyrrolidine-1-carbonyl)piperidin-3-yl)acetamido)pentylcarbamate

SMILES ONC(=O)[C@H]1CC(CC(=O)NCCCCCNC(=O)OCc2ccccc2)CN[C@@H]1C(=O)N1CCC(C1)c1ccccc1

InChI Key InChIKey=KMMSPMPORWBMTE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50268904   

TargetMatrix metalloproteinase-9(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50268904(benzyl 5-(2-((3RS,5S,6S)-5-(hydroxycarbamoyl)-6-(3...)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of human MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50268904(benzyl 5-(2-((3RS,5S,6S)-5-(hydroxycarbamoyl)-6-(3...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50268904(benzyl 5-(2-((3RS,5S,6S)-5-(hydroxycarbamoyl)-6-(3...)
Affinity DataIC50: 137nMAssay Description:Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50268904(benzyl 5-(2-((3RS,5S,6S)-5-(hydroxycarbamoyl)-6-(3...)
Affinity DataIC50: 302nMAssay Description:Inhibition of human recombinant ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50268904(benzyl 5-(2-((3RS,5S,6S)-5-(hydroxycarbamoyl)-6-(3...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50268904(benzyl 5-(2-((3RS,5S,6S)-5-(hydroxycarbamoyl)-6-(3...)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed