BDBM50268783 CHEMBL496606::N-(2,6-dimethylbenzyl)-2,3-dimethyl-6-(1H-1,2,4-triazol-1-yl)imidazo[1,2-a]pyridin-8-amine

SMILES Cc1nc2c(NCc3c(C)cccc3C)cc(cn2c1C)-n1cncn1

InChI Key InChIKey=YCAMYJGGAXTJHA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50268783   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268783(N-(2,6-dimethylbenzyl)-2,3-dimethyl-6-(1H-1,2,4-tr...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268783(N-(2,6-dimethylbenzyl)-2,3-dimethyl-6-(1H-1,2,4-tr...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268783(N-(2,6-dimethylbenzyl)-2,3-dimethyl-6-(1H-1,2,4-tr...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268783(N-(2,6-dimethylbenzyl)-2,3-dimethyl-6-(1H-1,2,4-tr...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268783(N-(2,6-dimethylbenzyl)-2,3-dimethyl-6-(1H-1,2,4-tr...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268783(N-(2,6-dimethylbenzyl)-2,3-dimethyl-6-(1H-1,2,4-tr...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed