BDBM50268744 (R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(1H-indol-3-yl)-2-oxoacetamide::CHEMBL495592

SMILES O=C(N[C@@H]1CCc2ccccc12)C(=O)c1c[nH]c2ccccc12

InChI Key InChIKey=HPOOEGNMALNZJV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50268744   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50268744((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(1H-indol-3-yl...)
Affinity DataKi:  225nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Rat)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50268744((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(1H-indol-3-yl...)
Affinity DataKi:  2.16E+3nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A alpha-5-beta-3-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50268744((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(1H-indol-3-yl...)
Affinity DataKi:  2.16E+3nMAssay Description:Inhibition of [3H]flumazenil binding to rat alpha-5-beta-3-gamma-2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rat)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50268744((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(1H-indol-3-yl...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A alpha-2-beta-2-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed