BDBM50268743 5-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo[1,2-a]pyridin-6-yl)pyrimidine-2,4(1H,3H)-dione::CHEMBL496806

SMILES Cc1nc2c(NCc3c(C)cccc3C)cc(cn2c1C)-c1c[nH]c(=O)[nH]c1=O

InChI Key InChIKey=QSPSYONCWQHOSB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50268743   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268743(5-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268743(5-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268743(5-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268743(5-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268743(5-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268743(5-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed