BDBM50268574 CHEMBL498423::Sodium 1-Amino-4-(1-naphthylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate::Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10 dihydroanthracene-2-sulfonate

SMILES Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2cccc3ccccc23)cc1S([O-])(=O)=O

InChI Key InChIKey=ZHQRPIRGSWEALJ-UHFFFAOYSA-M

Data  5 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50268574   

TargetP2Y purinoceptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataIC50: 6.67E+3nMAssay Description:Antagonist activity at human P2Y2 receptor expressed in astrocytoma cells assessed as inhibition of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 4(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataIC50: 1.01E+4nMAssay Description:Antagonist activity at human P2Y4 receptor expressed in astrocytoma cells assessed as inhibition of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat P2Y6 receptor expressed in astrocytoma cells assessed as inhibition of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against rat P2X2 receptor expressed in Xenopus laevis oocyte assessed as inhibition of alpha, beta-meATP-induced inward current b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetP2X purinoceptor 4(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against rat P2X4 receptor expressed in Xenopus laevis oocyte assessed as inhibition of alpha, beta-meATP-induced inward current b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetP2Y purinoceptor 4(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataIC50: 7.42E+3nMAssay Description:Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataKi:  530nMAssay Description:Inhibition of rat ecto-5'-nucleotidase expressed in Sf9 cells by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetNucleoside triphosphate diphosphohydrolase 3(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of rat NTPdase3 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PSB0413 from human platelet P2Y12 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataKi: >1.50E+5nMAssay Description:Inhibition of rat NTPdase1 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataKi: >4.00E+5nMAssay Description:Inhibition of rat NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed