BDBM50268557 9-(3-hydroxypropyl)-6-(3-(thiophen-3-yl)benzylamino)-9H-purine-2-carbonitrile::CHEMBL497237

SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccsc3)nc(nc12)C#N

InChI Key InChIKey=ROQSYDCGYWIBSQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268557   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California

Curated by ChEMBL
LigandPNGBDBM50268557(9-(3-hydroxypropyl)-6-(3-(thiophen-3-yl)benzylamin...)
Affinity DataIC50: 240nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50268557(9-(3-hydroxypropyl)-6-(3-(thiophen-3-yl)benzylamin...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50268557(9-(3-hydroxypropyl)-6-(3-(thiophen-3-yl)benzylamin...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed