BDBM50268545 CHEMBL4077787

SMILES Cc1c(C)c(OCc2csnc2-c2ccc(Cl)cc2)ccc1CCC(O)=O

InChI Key InChIKey=TWJRALVZUZRXFS-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50268545   

TargetFree fatty acid receptor 4(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50268545(CHEMBL4077787)
Affinity DataEC50:  217nMAssay Description:Agonist activity at human GPR120 short splice variant expressed in HEK293 cells assessed as increase in intracellular calcium flux by Fluo-4 NW dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50268545(CHEMBL4077787)
Affinity DataEC50:  1.34E+3nMAssay Description:Agonist activity at human GPR120 expressed in CHO-K1 cells assessed as increase in intracellular calcium flux by DiscoveRx PathHunter beta-arrestin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50268545(CHEMBL4077787)
Affinity DataEC50:  1.34E+3nMAssay Description:Agonist activity at PK-tagged human GPR120 long isoform expressed in CHOK1 cells co-expressing EA-tagged beta-arrestin assessed as beta-gal enzyme co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50268545(CHEMBL4077787)
Affinity DataEC50:  215nMAssay Description:Agonist activity at human GPR120 short splice variant expressed in HEK293 cells assessed as increase in intracellular calcium flux incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2020
Entry Details Article
PubMed