BDBM50268405 CHEMBL4068075

SMILES Sc1nnc(-c2ccc(cc2)\N=C\c2ccc(Cl)cc2)n1\N=C\c1ccc(Cl)cc1

InChI Key InChIKey=XQUWWQDADIPFPE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268405   

TargetDihydrofolate reductase(Bovine)
P.D. Patel Institute of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50268405(CHEMBL4068075)
Affinity DataIC50: 35nMAssay Description:Inhibition of bovine liver DHFR pre-incubated 2 mins before dihydrofolic acid substrate addition and measured over 10 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed