BDBM50268402 CHEMBL4101493

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=IMQJPHJIOZUTFU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268402   

TargetProteasome subunit beta type-5(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50268402(CHEMBL4101493)
Affinity DataIC50: 18nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human HL60 cells using Suc-LLVYaminoluciferin as substrate pretreated for 2 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50268402(CHEMBL4101493)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of trypsin-like activity of 20S proteasome in human HL60 cells using Z-LRRaminoluciferin as substrate pretreated for 2 hrs followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50268402(CHEMBL4101493)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human HL60 cells using Z-nLPnLDaminoluciferin as substrate pretreated for 2 hrs followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed