BDBM50268333 CHEMBL4084564

SMILES CCCn1cnc2c(cc(nc12)-c1ccc(NC(=O)NCC)cc1)N1CCOC[C@@H]1C

InChI Key InChIKey=MNOWCABUEYBUCD-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268333   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50268333(CHEMBL4084564)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using lipid substrate by Kinase-Glo plus luminescence kinase assay or and ADP-Glo Plus luminescence kinase a...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/4/2020
Entry Details Article
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TargetSerine/threonine-protein kinase mTOR(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50268333(CHEMBL4084564)Copy SMILESCopy InChI

Affinity DataIC50: 290nMAssay Description:Inhibition of mTOR (unknown origin) by Kinase-Glo plus luminescence kinase assay or and ADP-Glo Plus luminescence kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/4/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL