BDBM50268290 1,7-Dihydroxyxanthone::CHEBI:4946::CHEMBL389166

SMILES Oc1ccc2oc3cccc(O)c3c(=O)c2c1

InChI Key InChIKey=KDXFPEKLLFWHMN-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50268290   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Vnuhcm-University of Science

Curated by ChEMBL
LigandPNGBDBM50268290(CHEBI:4946 | 1,7-Dihydroxyxanthone | CHEMBL389166)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant PTP1B pre-incubated for 10 mins before pnitrophenyl phosphate substrate addition and measured every 30 secs for 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50268290(CHEBI:4946 | 1,7-Dihydroxyxanthone | CHEMBL389166)
Affinity DataIC50: 5.25E+4nMAssay Description:Inhibition of wild type H1N1 swine influenza virus neuraminidase using 4-MU-NANA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50268290(CHEBI:4946 | 1,7-Dihydroxyxanthone | CHEMBL389166)
Affinity DataIC50: 9.64E+4nMAssay Description:Inhibition of Influenza A virus H9N2 neuraminidase using 4-MU-NANA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50268290(CHEBI:4946 | 1,7-Dihydroxyxanthone | CHEMBL389166)
Affinity DataIC50: 5.69E+4nMAssay Description:Inhibition of oseltamivir-resistant H1N1 swine influenza virus neuraminidase H274Y mutant using 4-MU-NANA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50268290(CHEBI:4946 | 1,7-Dihydroxyxanthone | CHEMBL389166)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of Influenza A virus H1N1 neuraminidase using 4-MU-NANA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetTyrosinase(Human)
Universidade Dos A£Ores

Curated by ChEMBL
LigandPNGBDBM50268290(CHEBI:4946 | 1,7-Dihydroxyxanthone | CHEMBL389166)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of Tyrosinase (unknown origin) using tyrosine as substrate incubated for 20 mins followed by substrate addition and measured every 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca

Curated by ChEMBL
LigandPNGBDBM50268290(CHEBI:4946 | 1,7-Dihydroxyxanthone | CHEMBL389166)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using PNPG as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Polytechnic Institute of Braganca

Curated by ChEMBL
LigandPNGBDBM50268290(CHEBI:4946 | 1,7-Dihydroxyxanthone | CHEMBL389166)
Affinity DataIC50: 36nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as release of p-nitrophenol using pNPG as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed