BDBM50268180 1-Ethyl-8-(4-(4-(4-methylbenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione::CHEMBL520617

SMILES CCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(=O)(=O)N1CCN(Cc2ccc(C)cc2)CC1

InChI Key InChIKey=BGRKVIAGBNUFJB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50268180   

TargetAdenosine receptor A2b(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50268180(1-Ethyl-8-(4-(4-(4-methylbenzyl)piperazine-1-sulfo...)
Affinity DataKi:  1.58nMAssay Description:Displacement of [3H]PSB-603 from human recombinant adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50268180(1-Ethyl-8-(4-(4-(4-methylbenzyl)piperazine-1-sulfo...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]CCPA from rat brain cortex adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50268180(1-Ethyl-8-(4-(4-(4-methylbenzyl)piperazine-1-sulfo...)
Affinity DataKi:  341nMAssay Description:Displacement of [3H]MSX-2 from rat brain striatum adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50268180(1-Ethyl-8-(4-(4-(4-methylbenzyl)piperazine-1-sulfo...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PSB-11 from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed