BDBM50268017 CHEMBL4088739

SMILES COc1n[nH]c2ncc(cc12)C#Cc1c(F)ccc(NS(=O)(=O)c2cccc(Cl)c2Cl)c1F

InChI Key InChIKey=PVDAJIQBDSEKPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268017   

TargetMitogen-activated protein kinase kinase kinase 20(Human)
University of Macau

Curated by ChEMBL
LigandPNGBDBM50268017(CHEMBL4088739)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full-length ZAK expressed in baculovirus infected Sf9 insect cells using MBP as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University of Macau

Curated by ChEMBL
LigandPNGBDBM50268017(CHEMBL4088739)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of wild type GST-tagged recombinant human full-length B-RAF expressed in baculovirus expression system using Ser/Thr3 as substrate after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed