BDBM50267904 CHEMBL504182::cyclohexyl((2R,6S)-2,6-dimethyl-4-(naphthalen-1-ylsulfonyl)piperazin-1-yl)methanone

SMILES C[C@H]1CN(C[C@@H](C)N1C(=O)C1CCCCC1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=CGDKNZWDQQQYIK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267904   

TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267904(cyclohexyl((2R,6S)-2,6-dimethyl-4-(naphthalen-1-yl...)
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267904(cyclohexyl((2R,6S)-2,6-dimethyl-4-(naphthalen-1-yl...)
Affinity DataEC50:  8nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed