BDBM50267871 CHEMBL489852::cyclohexyl(4-(naphthalen-1-ylsulfonyl)-2-(trifluoromethyl)piperazin-1-yl)methanone

SMILES FC(F)(F)C1CN(CCN1C(=O)C1CCCCC1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=VUPNCHYSPJAHKY-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267871   

TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267871(cyclohexyl(4-(naphthalen-1-ylsulfonyl)-2-(trifluor...)
Affinity DataIC50: 290nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267871(cyclohexyl(4-(naphthalen-1-ylsulfonyl)-2-(trifluor...)
Affinity DataEC50:  2.5nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed