BDBM50267870 CHEMBL489645::cyclohexyl(3-methyl-4-(naphthalen-1-ylsulfonyl)piperazin-1-yl)methanone

SMILES CC1CN(CCN1S(=O)(=O)c1cccc2ccccc12)C(=O)C1CCCCC1

InChI Key InChIKey=HHPMEXAKTRNDQM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267870   

TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267870(cyclohexyl(3-methyl-4-(naphthalen-1-ylsulfonyl)pip...)
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267870(cyclohexyl(3-methyl-4-(naphthalen-1-ylsulfonyl)pip...)
Affinity DataEC50:  180nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed