BDBM50267821 CHEMBL445204::cyclopropyl(4-(3,5-dichlorophenylsulfonyl)piperazin-1-yl)methanone

SMILES Clc1cc(Cl)cc(c1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1

InChI Key InChIKey=AYYDIDDDTKUDTB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267821   

TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267821(cyclopropyl(4-(3,5-dichlorophenylsulfonyl)piperazi...)
Affinity DataIC50: 780nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267821(cyclopropyl(4-(3,5-dichlorophenylsulfonyl)piperazi...)
Affinity DataEC50:  5nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed