BDBM50267819 CHEMBL522945::N-(1-(3,5-bis(trifluoromethyl)phenylsulfonyl)azetidin-3-yl)-2-(4-(trifluoromethyl)phenyl)acetamide

SMILES FC(F)(F)c1ccc(CC(=O)NC2CN(C2)S(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1

InChI Key InChIKey=OAFBBLQLICKSQI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267819   

TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267819(N-(1-(3,5-bis(trifluoromethyl)phenylsulfonyl)azeti...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267819(N-(1-(3,5-bis(trifluoromethyl)phenylsulfonyl)azeti...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed