BDBM50267774 CHEMBL523100::cyclohexyl(4-(naphthalen-1-ylsulfonyl)piperazin-1-yl)methanone

SMILES O=C(C1CCCCC1)N1CCN(CC1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=YCYPTKGWJASRLD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267774   

TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267774(cyclohexyl(4-(naphthalen-1-ylsulfonyl)piperazin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267774(cyclohexyl(4-(naphthalen-1-ylsulfonyl)piperazin-1-...)
Affinity DataIC50: 95nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267774(cyclohexyl(4-(naphthalen-1-ylsulfonyl)piperazin-1-...)
Affinity DataEC50:  0.600nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed