BDBM50267759 3-(6-Hydroxymethylbenzofuran-3-yl)-4-(7-hydroxymethyl-1-methyl-1H-indol-3-yl)pyrrole-2,5-dione::CHEMBL491447

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2coc3cc(CO)ccc23)c2cccc(CO)c12

InChI Key InChIKey=REWAULXFDBKSQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267759   

TargetGlycogen synthase kinase-3 beta(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267759(3-(6-Hydroxymethylbenzofuran-3-yl)-4-(7-hydroxymet...)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267759(3-(6-Hydroxymethylbenzofuran-3-yl)-4-(7-hydroxymet...)
Affinity DataIC50: 27nMAssay Description:Inhibition of CDK2/Cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed