BDBM50267627 CHEMBL4090805

SMILES CCOC(=O)Nc1ccc2OC(C)(C)CC(NC(=O)Nc3cccc(c3)C#N)c2c1

InChI Key InChIKey=XOYMNQRJKZCEKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267627   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267627(CHEMBL4090805)
Affinity DataIC50: 5.11E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267627(CHEMBL4090805)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed