BDBM50267587 1-(3-Chloro-4-methylphenyl)-3-(4-methyl-3-nitrophenyl)thiourea::CHEMBL489822

SMILES Cc1ccc(NC(=S)Nc2ccc(C)c(c2)[N+]([O-])=O)cc1Cl

InChI Key InChIKey=UVCVHWXKFNFLOI-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267587   

TargetPeptidyl-prolyl cis-trans isomerase A(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50267587(1-(3-Chloro-4-methylphenyl)-3-(4-methyl-3-nitrophe...)
Affinity DataIC50: 460nMAssay Description:Inhibition of human cyclophilin A at 6 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50267587(1-(3-Chloro-4-methylphenyl)-3-(4-methyl-3-nitrophe...)
Affinity DataKd:  8.89E+4nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed