BDBM50267547 1-(3-Chloro-4-methylphenyl)-3-(2-(2-(diethylamino)-6-methyl-5-nitropyrimidin-4-ylamino)ethyl)thiourea::CHEMBL518980

SMILES CCN(CC)c1nc(C)c(c(NCCNC(=S)Nc2ccc(C)c(Cl)c2)n1)[N+]([O-])=O

InChI Key InChIKey=ACBIPOZTZXTKMQ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267547   

TargetPeptidyl-prolyl cis-trans isomerase A(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50267547(1-(3-Chloro-4-methylphenyl)-3-(2-(2-(diethylamino)...)
Affinity DataKd:  7.33E+4nMAssay Description:Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50267547(1-(3-Chloro-4-methylphenyl)-3-(2-(2-(diethylamino)...)
Affinity DataIC50: 740nMAssay Description:Inhibition of human cyclophilin A at 6 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed