BDBM50267523 3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-hydroxymethylbenzofuran-3-yl)pyrrole-2,5-dione::CHEMBL522590

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2coc3cc(CO)ccc23)c2cc(F)c(Cl)cc12

InChI Key InChIKey=NZVVXITYPLCRRD-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50267523   

TargetCyclin-dependent kinase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267523(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of CDK2/Cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267523(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-...)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of CDK5/P35More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267523(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267523(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of CDK3/Cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267523(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-...)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of CDK4/Cyclin D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267523(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-...)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of CDK5/P25More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267523(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of CDK6/cyclin D3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267523(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of CDK9/cyclin T1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267523(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-...)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267523(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of CDK2/Cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed