BDBM50267486 CHEMBL478696::methyl 3-(trifluoromethyl)-5-(4-(2-(4-(trifluoromethyl)phenyl)acetyl)piperazin-1-ylsulfonyl)benzoate

SMILES COC(=O)c1cc(cc(c1)S(=O)(=O)N1CCN(CC1)C(=O)Cc1ccc(cc1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=GJGRAMGTQURCNW-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267486   

TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267486(methyl 3-(trifluoromethyl)-5-(4-(2-(4-(trifluorome...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267486(methyl 3-(trifluoromethyl)-5-(4-(2-(4-(trifluorome...)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267486(methyl 3-(trifluoromethyl)-5-(4-(2-(4-(trifluorome...)
Affinity DataEC50:  1nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed