BDBM50267405 CHEMBL478066::cyclopropyl(4-(2,4,6-trichlorophenylsulfonyl)piperazin-1-yl)methanone

SMILES Clc1cc(Cl)c(c(Cl)c1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1

InChI Key InChIKey=ZKOJGGOBCWAUBA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267405   

TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267405(cyclopropyl(4-(2,4,6-trichlorophenylsulfonyl)piper...)
Affinity DataIC50: 9.70E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267405(cyclopropyl(4-(2,4,6-trichlorophenylsulfonyl)piper...)
Affinity DataEC50:  1.50E+3nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed