BDBM50267164 CHEMBL4068098

SMILES Cc1nncn1C1CCN(Cc2cc3nc(nc(N4CCOCC4)c3s2)-c2cccc(O)c2)CC1

InChI Key InChIKey=TTZDHGDYMSKHEK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50267164   

LigandPNGBDBM50267164(CHEMBL4068098)
Affinity DataIC50: 100nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed
LigandPNGBDBM50267164(CHEMBL4068098)
Affinity DataIC50: 200nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed
LigandPNGBDBM50267164(CHEMBL4068098)
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed
LigandPNGBDBM50267164(CHEMBL4068098)
Affinity DataIC50: 158nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed