BDBM50267134 CHEMBL4092258

SMILES [H][C@@]12CCc3nnc(n3[C@@]1([H])CCN(Cc1cc3nc(nc(N4CCOCC4)c3s1)-c1cccc3[nH]ncc13)C2)C(F)(F)F

InChI Key InChIKey=DNTVVJQBGDJUBK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50267134   

LigandPNGBDBM50267134(CHEMBL4092258)
Affinity DataIC50: 631nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed
LigandPNGBDBM50267134(CHEMBL4092258)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed
LigandPNGBDBM50267134(CHEMBL4092258)
Affinity DataIC50: 158nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed
LigandPNGBDBM50267134(CHEMBL4092258)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed