BDBM50267133 CHEMBL4081998

SMILES [H][C@]12CCc3nnc(C)n3[C@@]1([H])CCN(Cc1cc3nc(nc(N4CCOCC4)c3s1)-c1cccc3[nH]ccc13)C2

InChI Key InChIKey=ZRNOFVLNBAYQHX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50267133   

LigandPNGBDBM50267133(CHEMBL4081998)
Affinity DataIC50: 316nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed
LigandPNGBDBM50267133(CHEMBL4081998)
Affinity DataIC50: 0.794nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed
LigandPNGBDBM50267133(CHEMBL4081998)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed
LigandPNGBDBM50267133(CHEMBL4081998)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details Article
PubMed