BDBM50267109 3-(3-hydroxy-4-methoxyphenyl)pyrrolo[2,3-b]pyrrolizin-8(1H)-one::CHEMBL518732

SMILES COc1ccc(cc1O)-c1c[nH]c2C(=O)c3cccn3-c12

InChI Key InChIKey=ZGMPTJKNNNXAHF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267109   

TargetCyclin-dependent kinase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50267109(3-(3-hydroxy-4-methoxyphenyl)pyrrolo[2,3-b]pyrroli...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50267109(3-(3-hydroxy-4-methoxyphenyl)pyrrolo[2,3-b]pyrroli...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50267109(3-(3-hydroxy-4-methoxyphenyl)pyrrolo[2,3-b]pyrroli...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed