BDBM50267051 CHEMBL4101348

SMILES COc1ccc(F)c(c1)-c1ccc(Cc2ccc(cc2)N2C[C@@H](C[C@H]2CC(O)=O)C(F)(F)F)c(C)c1

InChI Key InChIKey=PKUNNSLPQXPQEP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267051   

TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267051(CHEMBL4101348)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267051(CHEMBL4101348)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed