BDBM50267004 CHEMBL4096095

SMILES CC1=CC(=O)N(c2c1cc(c(c2)OC)NS(=O)(=O)c3ccc(cc3)C#N)C

InChI Key InChIKey=OHKRNOLZIOHQBM-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50267004   

TargetBromodomain-containing protein 1(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50267004(CHEMBL4096095)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human BRPF2-BRD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50267004(CHEMBL4096095)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human BRD4-BD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50267004(CHEMBL4096095)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human BRPF3 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 9(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50267004(CHEMBL4096095)
Affinity DataIC50: 890nMAssay Description:Inhibition of human BRD9 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetPeregrin(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50267004(CHEMBL4096095)
Affinity DataIC50: 60nMAssay Description:Inhibition of human BRPF1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)