BDBM50266957 CHEMBL2070024

SMILES CC(C)Cc1cc(ccc1OCC([O-])=O)-c1ccc(cc1Cc1ccccc1)-c1ccc(CCC([O-])=O)cc1CC(C)C

InChI Key InChIKey=MOTQYJLKPNIITG-UHFFFAOYSA-L

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266957   

TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50266957(CHEMBL2070024)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Bak BH3 peptide binding to GST-tagged human Bcl-xL after 3 hrs by Western blotting-based GST pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50266957(CHEMBL2070024)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of Bim BH3 peptide binding to GST-tagged human Mcl-1 after 3 hrs by Western blotting-based GST pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50266957(CHEMBL2070024)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of GST-tagged Bcl-xL (unknown origin) after 3 hrs by pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50266957(CHEMBL2070024)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of GST-tagged MCl-1 (unknown origin) after 3 hrs by pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed